Claude Opus 4 vs InternVL 2.5 78B

Compare Claude Opus 4 and InternVL 2.5 78B: pricing, performance, context window, latency, and best use cases. Side-by-side comparison on XALEN.

Updated 2026-05-21 · By Abhishek Raj · Our methodology

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Feature Claude Opus 4 InternVL 2.5 78B
CategoryFrontierVision
Parameters~2T78B
Context Window200K128K
Input Price$0.15/1M tokens$0.05/1M tokens
Output Price$0.75/1M tokens$0.10/1M tokens
Latency~800ms~400ms

Choose Claude Opus 4 when:

  • ✓ Complex counseling
  • ✓ Detailed chart analysis
  • ✓ Enterprise reports
Key Strengths:

Deepest reasoning, Exceptional nuance, Best complex analysis

Choose InternVL 2.5 78B when:

  • ✓ Document analysis
  • ✓ Chart reading
  • ✓ Visual Q&A
Key Strengths:

Strong visual reasoning, Open weights, Good OCR

Verdict: Claude Opus 4 vs InternVL 2.5 78B

For cost efficiency, InternVL 2.5 78B wins at $0.05/1M input tokens. For speed, InternVL 2.5 78B is faster at ~400ms. Claude Opus 4 excels at Complex counseling while InternVL 2.5 78B is better for Document analysis. Both are available on XALEN through a single API — try them in the Playground to see which fits your workload.

Detailed Analysis

Pricing Comparison

Claude Opus 4 costs $0.15/1M input tokens and $0.75/1M output tokens. InternVL 2.5 78B costs $0.05 input and $0.10 output. InternVL 2.5 78B is 3.0x cheaper on input tokens. XALEN offers batch processing at 50% discount on both models.

Performance & Context

Claude Opus 4 has a 200K context window with ~800ms latency. InternVL 2.5 78B offers 128K context at ~400ms. Claude Opus 4 has the larger context window.

Best For

Claude Opus 4 (Frontier) is optimized for: Complex counseling, Detailed chart analysis, Enterprise reports. InternVL 2.5 78B (Vision) works best for: Document analysis, Chart reading, Visual Q&A.

Try Both on XALEN

Both models are available through XALEN's OpenAI-compatible API. Switch between them by changing the model parameter:

from xalen import XALEN

client = XALEN(api_key="xln_test_YOUR_KEY")

# Use Claude Opus 4
response_a = client.chat.completions.create(
    model="claude-opus-4",
    messages=[{"role": "user", "content": "Your question here"}]
)

# Use InternVL 2.5 78B
response_b = client.chat.completions.create(
    model="internvl-2-5-78b",
    messages=[{"role": "user", "content": "Your question here"}]
)

Start Building with XALEN

200+ AI models. One API. Pay-as-you-go.

Get API Key Try in Playground

Frequently Asked Questions

Which is better, Claude Opus 4 or InternVL 2.5 78B?

Claude Opus 4 (Frontier, ~2T) offers Deepest reasoning. InternVL 2.5 78B (Vision, 78B) offers Strong visual reasoning. Choose Claude Opus 4 for Complex counseling or InternVL 2.5 78B for Document analysis.

How much does Claude Opus 4 cost vs InternVL 2.5 78B?

Claude Opus 4: $0.15/1M input, $0.75/1M output. InternVL 2.5 78B: $0.05/1M input, $0.10/1M output. Both available on XALEN with batch processing at 50% discount.

Can I use both models on XALEN?

Yes. XALEN provides 200+ models through a single OpenAI-compatible API. Switch between Claude Opus 4 and InternVL 2.5 78B by changing the model parameter. No code changes needed.

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Last updated: 2026-05-21. Pricing and specifications may change. Check pricing page for latest rates.