Claude Opus 4.5 vs InternVL 2.5 78B

Compare Claude Opus 4.5 and InternVL 2.5 78B: pricing, performance, context window, latency, and best use cases. Side-by-side comparison on XALEN.

Updated 2026-05-21 · By Abhishek Raj · Our methodology

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Feature Claude Opus 4.5 InternVL 2.5 78B
CategoryFrontierVision
Parameters~2.5T78B
Context Window200K128K
Input Price$0.15/1M tokens$0.05/1M tokens
Output Price$0.75/1M tokens$0.10/1M tokens
Latency~900ms~400ms

Choose Claude Opus 4.5 when:

  • ✓ Creative writing
  • ✓ Complex analysis
  • ✓ Research
Key Strengths:

Superior creativity, Nuanced reasoning, Complex analysis

Choose InternVL 2.5 78B when:

  • ✓ Document analysis
  • ✓ Chart reading
  • ✓ Visual Q&A
Key Strengths:

Strong visual reasoning, Open weights, Good OCR

Verdict: Claude Opus 4.5 vs InternVL 2.5 78B

For cost efficiency, InternVL 2.5 78B wins at $0.05/1M input tokens. For speed, InternVL 2.5 78B is faster at ~400ms. Claude Opus 4.5 excels at Creative writing while InternVL 2.5 78B is better for Document analysis. Both are available on XALEN through a single API — try them in the Playground to see which fits your workload.

Detailed Analysis

Pricing Comparison

Claude Opus 4.5 costs $0.15/1M input tokens and $0.75/1M output tokens. InternVL 2.5 78B costs $0.05 input and $0.10 output. InternVL 2.5 78B is 3.0x cheaper on input tokens. XALEN offers batch processing at 50% discount on both models.

Performance & Context

Claude Opus 4.5 has a 200K context window with ~900ms latency. InternVL 2.5 78B offers 128K context at ~400ms. Claude Opus 4.5 has the larger context window.

Best For

Claude Opus 4.5 (Frontier) is optimized for: Creative writing, Complex analysis, Research. InternVL 2.5 78B (Vision) works best for: Document analysis, Chart reading, Visual Q&A.

Try Both on XALEN

Both models are available through XALEN's OpenAI-compatible API. Switch between them by changing the model parameter:

from xalen import XALEN

client = XALEN(api_key="xln_test_YOUR_KEY")

# Use Claude Opus 4.5
response_a = client.chat.completions.create(
    model="claude-opus-4-5",
    messages=[{"role": "user", "content": "Your question here"}]
)

# Use InternVL 2.5 78B
response_b = client.chat.completions.create(
    model="internvl-2-5-78b",
    messages=[{"role": "user", "content": "Your question here"}]
)

Start Building with XALEN

200+ AI models. One API. Pay-as-you-go.

Get API Key Try in Playground

Frequently Asked Questions

Which is better, Claude Opus 4.5 or InternVL 2.5 78B?

Claude Opus 4.5 (Frontier, ~2.5T) offers Superior creativity. InternVL 2.5 78B (Vision, 78B) offers Strong visual reasoning. Choose Claude Opus 4.5 for Creative writing or InternVL 2.5 78B for Document analysis.

How much does Claude Opus 4.5 cost vs InternVL 2.5 78B?

Claude Opus 4.5: $0.15/1M input, $0.75/1M output. InternVL 2.5 78B: $0.05/1M input, $0.10/1M output. Both available on XALEN with batch processing at 50% discount.

Can I use both models on XALEN?

Yes. XALEN provides 200+ models through a single OpenAI-compatible API. Switch between Claude Opus 4.5 and InternVL 2.5 78B by changing the model parameter. No code changes needed.

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Last updated: 2026-05-21. Pricing and specifications may change. Check pricing page for latest rates.